The ADVANCE Clinical Data Research Network (CDRN) is led by OCHIN in partnership with Health Choice Network (HCN) and Fenway Health. The goal of ADVANCE is to build and maintain a “community laboratory” of health centers across the country that serve safety net patients, including the uninsured, the under-insured, low income individuals and families, immigrants, and other vulnerable populations. ADVANCE seeks to partner with any researchers interested in carrying out high-quality research with the goal of improving the care and health outcomes of safety net and vulnerable patients and their communities.


Integrate outpatient, hospital, and community-level data into a single data management system


Expand efforts to engage patients and clinicians who contribute to the design, implementation, and interpretation of comparative effectiveness research

Develop electronic systems for recruiting study participants and collecting patient-reported data

Strengthen the infrastructure of our community academic partnerships to support patient-centered outcomes research (PCOR), and support FQHCs to become learning health systems

Build the capacity of our FQHC networks to meet research regulatory requirements.

It is anticipated that ADVANCE will result in greatly expanded capacity to conduct comparative effectiveness research in the safety net population, and allow for collaboration with diverse partners on such efforts. It will also yield the nation’s largest database on safety net patient care and outcomes. Research conducted in this dataset has the potential to address myriad questions about improving care quality and outcomes among our nation’s most vulnerable patients.